About Diazem

Corporate Profile

Since 1994, the Diazem™ Corporation has been a manufacturer and supplier of specialty separation sorbents used in high-performance liquid chromatography (HPLC) within the water treatment, pharmaceutical & biopharmaceutical, chemical & fine chemical, agrochemical, mining and food processing industries. We have also developed the capability to address the most challenging environmental remediation issues.

Located in Midland, Michigan, Diazem was the original marketer of Dual Zone™ Materials (DZM). DZM adsorbents can separate diverse materials out of complex liquid broths more completely and efficiently than can other commercially available separations media. DZM technology uses state of the art organosilane chemistry to selectively modify the exterior surface of porous HPLC grade silica with an initial silane while leaving the interior surface unreacted. In a second step the interior surface is modified with a different silane. The result is a bonded silica particle with two distinct phases. The permutations available for DZM chemistries are countless when one considers the possible range of lipophilic, lipophobic, hydrophilic, nonionic, ionic and other silane chemistries.

Diazem has also developed the ability to tailor the electronic properties of a bonded silica surface (in addition to the hydrophobic properties), thereby extending still further its ability to tailor and control the bonded phase chemistries of its HPLC products to solve highly specific and custom solutions to difficult separations problems. These chemistries extend beyond simple modification of the main phase to provide a broader range of separation capabilities. Diazem controls hydrophobicity and secondary electronic properties of the media surface to produce phases that give truly unique and powerful separation capabilities. An added advantage is that Diazem phases give excellent performance on neutral, acidic, and basic analytes for small molecules and macro molecules.

Corporate Vision

The Vision of Diazem Corporation is to become a recognized global technology leader of tailored adsorbents serving the needs of the separations industry.